Research progress on irradiation sterilization of traditional Chinese medicine
10.12173/j.issn.2097-4922.202404147
- VernacularTitle:中药辐照灭菌研究进展
- Author:
Chen YANG
1
,
2
;
Yuxiao ZHENG
;
Xinyuan XU
;
Yuehui LI
Author Information
1. 湖南省中医药研究院,长沙 410013
2. 湖南中医药大学,长沙 410208
- Keywords:
Irradiation sterilization;
60Co-γ ray;
Electron beam;
Traditional Chinese medicine;
Microorganisms;
Chemical constituents;
Effectiveness
- From:
China Pharmacist
2024;28(10):331-340
- CountryChina
- Language:Chinese
-
Abstract:
Sterilization is one of the key links in the production of traditional Chinese medicine,and it is also an important factor to ensure the safety,effectiveness and quality control of traditional Chinese medicine.Traditional sterilization techniques such as moist heat sterilization are limited in many cases due to their inherent shortcomings.In contrast,irradiation sterilization has attracted more and more attention due to its advantages of fast,efficient,strong sterilization and low cost.However,the chemical composition of traditional Chinese medicine is complex,due to the radioactivity and strong penetration of irradiation,after a certain dose of irradiation,its chemical composition and pharmacological activity may change.At present,there is still a lack of systematic research on the changes of chemical composition,effectiveness and safety of traditional Chinese medicine after irradiation sterilization.Based on the research status of 60Co-γ ray and electron beam irradiation sterilization in the sterilization of traditional Chinese medicine in recent years,this paper reviews the effects of irradiation on the effectiveness of traditional Chinese medicine,the detection methods of irradiation and the safety evaluation,in order to provide some reference for the subsequent application of irradiation sterilization of traditional Chinese medicine.
