Analysis of short-and long-term clinical effect of traditional Chinese medicine rolling egg therapy in treating infantile diarrhea
10.12173/j.issn.2097-4922.202407132
- VernacularTitle:中药滚蛋疗法治疗小儿腹泻的近远期临床效果分析
- Author:
Yuxia HUANG
1
;
Lijiao LUO
;
Huizhen YUAN
;
Fengjing ZHU
;
Shujun CAI
Author Information
1. 南方医科大学第十附属医院(东莞市人民医院)小儿内科,广东东莞523000
- Keywords:
Integration of traditional Chinese and western medicine;
Infantile diarrhea;
Rolling egg therapy;
Inflammatory factors;
Long-term efficacy;
Immunoglobulin;
Tumor necrosis factor;
Clinical effect
- From:
China Pharmacist
2024;28(10):237-244
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application effect of traditional Chinese medicine rolling egg therapy in the treatment of infantile diarrhea.Methods A retrospective analysis was conducted on the clinical data of children with diarrhea in Dongguan People's Hospital from April 2022 to April 2024.According to the treatment methods,they were divided into the control group and the combination group.The control group was treated with western medicine,while the combination group was combined with traditional Chinese medicine rolling egg therapy on the basis of the control group.7 d was a course of treatment,and a total of 2 courses of treatment was conducted.The clinical efficacy was evaluated,and the durations of clinical symptom changes after treatment were compared.The intestinal flora,immune function[immunoglobulin (Ig) A,IgG,IgM]and inflammatory factors[interleukin (IL)-6,IL-17,tumor necrosis factor (TNF) α]were observed before and after treatment.The treatment safety was analyzed,and the recurrence within 6 months of follow-up was counted.Results A total of 180 patients were included in the study,with 106 in the control group and 74 in the combination group.The total effective rate of the combination group was higher than that of the control group (P<0.05).After treatment,the time to stop diarrhea,reduce fever and change stool properties to normal in the combination group was lower than that in the control group (P<0.05);the number of Bifidobacteria and Lactobacilli in both groups was higher than that before treatment,and the number of combination group was higher than that of the control group (P<0.05);the number of Enterococcus faecalis and the levels of TNF-α,IL-6 and IL-17 were lower than those before treatment in both groups,and these in the combination group were lower than those in the control group (P<0.05);the levels of IgA,IgG and IgM were higher than those before treatment in the combination group (P<0.05),and the IgA level was significantly higher than that of the control group (P<0.05).At 6 months,the recurrence rate of the combination group was lower than that of the control group (P<0.05).Conclusion Traditional Chinese medicine rolling egg therapy combined with western medicine is effective in the treatment of children with diarrhea,and its mechanism may be related to the improvement of immune function,inflammatory response and intestinal flora.
