Research progress on chemical components and pharmacological effects of polyalkynes in Atractylodis rhizoma
10.12173/j.issn.2097-4922.202403173
- VernacularTitle:苍术中聚炔类化学成分及其药理作用研究进展
- Author:
Yunjing XING
1
;
Guoxu MA
;
Zhanming XU
;
Xiaowei ZHU
;
Junhao NIE
;
Zhiquan ZHANG
;
Xudong XU
Author Information
1. 中国医学科学院北京协和医学院药用植物研究所(北京 100000)
- Keywords:
Atractylodis rhizoma;
Polyalkynes;
Chemical components;
Volatile oils;
Alkynes;
Glycosides;
Pharmacological effects;
Research progress
- From:
China Pharmacist
2024;28(9):109-123
- CountryChina
- Language:Chinese
-
Abstract:
Atractylodis rhizoma is a perennial herb of the Asteraceae family,which mainly divided into A.chinensis(DC)Koidz and Atractyiodes lancea(Thunb)DC,with the effects of strengthening the spleen,drying dampness,brightening the eyes,etc.Atractylodis rhizoma is mainly used in the clinical treatment of spleen deficiency and dampness,night blindness,eye fatigue and other symptoms.According to the clinical effect,and modern pharmacological researches have confirmed,the Chinese herbal medicine Atractylodis rhizoma contains a variety of active ingredients,such as volatile oils,alkynes,glycosides,etc.In recent years,pharmacological studies on Atractylodis rhizoma have found that atractylodin in polyalkynes has good activity in anti-inflammation,treatment of bacterial resistance,and inhibition of cholangiocarcinoma cell migration,and its high biological activity may be related to the conjugated enyne structure.Therefore,this article summarizes the studies on chemical components and pharmacological effects of polyalkynes in Atractylodis rhizoma that have been published in recent years,and comprehensively expounds the research progress of polyalkynes in Atractylodis rhizoma,so as to provide reference for scientific researchers and promote the in-depth development and utilization of the medicinal value of Atractylodis rhizoma.
