Study on the management strategy of anticancer drugs in pharmacy intravenous admixture services based on failure mode and effect analysis
10.12173/j.issn.1008-049X.202401197
- VernacularTitle:基于失效模式和效应分析的静脉用药调配中心抗肿瘤药物管理策略研究
- Author:
Dianli YANG
1
;
Jing LI
;
Yajing YU
Author Information
1. 芜湖市第一人民医院药剂科(安徽芜湖 241000)
- Keywords:
Failure mode;
Effect analysis;
Pharmacy intravenous admixture services;
Antitumor drug;
Drug administration
- From:
China Pharmacist
2024;27(5):841-847
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application of failure mode and effect analysis(FMEA)to analyze the risk status of antitumor drugs in pharmacy intravenous admixture services(PIVAS),implement preventive measures,and to improve the drug safety.Methods FMEA method was used to analyze the risks of different failure modes in the management of antitumor drugs in PIVAS of Wuhu First People's Hospital,and the risk priority value(RPN)scores were calculated respectively.Taking RPN≥216 points as the medium and high risk points,effective preventive measures were taken for them,and the effects before and after the implementation of preventive measures were observed.Results After comprehensive analysis,8 medium and high risk points were identified,including failure to carefully check the returned drugs,insufficient identification of drugs,failure to strictly implement the verification system,mixing of drugs before complete dissolution,incompatibility,wrong placement of drugs,failure to check and seal non-whole drugs by two people,and incorrect verification process.After the preventive measures were taken,the RPN score of the medium and high risk points of the 8 items before implementation was(271.88±33.97)points,the RPN score of the medium and high risk points of the 8 items after implementation was(76.25±28.38)points and there was a statistical difference between them(P<0.05).Compared with before implementation of preventive measures,deployment error rate after implementation was lower(P<0.05).Conclusion FMEA method can effectively prevent risks and reduce the error rate of anti-tumor drug dispensing,thus ensuring the safety of medical staff and patients.
