Application of process analytical technology in advanced manufacturing of dermal drug delivery products
10.19778/j.chp.2024.02.001
- VernacularTitle:过程分析技术在皮肤递药制剂先进制造中的应用
- Author:
Yidian WANG
1
,
2
;
Huafei LUO
Author Information
1. 中国医药工业研究总院医药先进制造国家工程研究中心,上海 201203
2. 中国药科大学药学院药剂系,南京 211198
- Keywords:
continuous manufacturing;
process analytical technology;
critical quality attributes;
dermal drug deliv-ery products;
chemometrics
- From:
Drug Standards of China
2024;25(2):109-117
- CountryChina
- Language:Chinese
-
Abstract:
Process analysis technology(PAT)is of great significance to improve the process control and quality as-surance in the manufacture of dermal drug delivery products.This paper reviewed the application of PAT technology in the advanced manufacturing of dermal drug delivery products,introduced the basic situation of PAT and chemo-metrics,and summarized the commonly used PAT tools and their application examples in recent years.In the fu-ture,PAT will play a greater role in the process ofdermal drug delivery products,but the research in this area is still very scarce now.
