Environmental RNA applications in ecological risk assessment of chemicals
10.3867/j.issn.1000-3002.2024.10.005
- VernacularTitle:环境RNA在化学物质生态风险评估中的应用及展望
- Author:
Xiao GOU
1
;
Xinxin SU
;
Qiong WANG
;
Xianglin LIU
;
Huimin JI
;
Xiaowei ZHANG
Author Information
1. 南京大学环境学院,国家环境保护长江中下游水生态健康重点实验室,江苏南京 210023
- Keywords:
environmental RNA;
chemical pollution;
toxicity tests;
risk assessment;
ecological effect
- From:
Chinese Journal of Pharmacology and Toxicology
2024;38(10):759-765
- CountryChina
- Language:Chinese
-
Abstract:
Chemical pollution-induced damage to ecosystem function has been a global challenge.The latest"Kunming-Montreal Global Biodiversity Framework"proposed reducing pollution risks to levels harmless to biodiversity and function,placing higher demands on chemical risk management at the ecosystem level.Conventional ecotoxicity tests have focused on single species,only to neglect genetic diversity protection and simplify species interactions.Here,we proposed using environmental RNA(eRNA)and metatranscriptomic analysis to establish a multi-species,multi-biological level chemical pollution ecological risk assessment approach in exposed communities.We reviewed the current status and trends of eRNA in chemical pollution risk assessment and proposed a strategy for bioeffect testing from molecules to communities based on eRNA,constructing ecological risk assessment models for different protection goals.Finally,we summarized the theoretical and technical challenges facing eRNA-based toxicity testing and outlined the future applications of eRNA in capturing real ecological effects of chemical pollution in the field.
