Alternative toxicity testing and progress in applications of cosmetics safety risk assessment
10.3867/j.issn.1000-3002.2024.10.001
- VernacularTitle:毒性测试替代方法及其在化妆品安全风险评估中应用进展
- Author:
Feifei XU
1
;
Xiaohan ZHAO
;
Meng ZHOU
;
Siyu WAN
;
Xiaoxuan XIAO
;
Jia SONG
;
Xingfen YANG
Author Information
1. 南方医科大学公共卫生学院,食物安全与健康研究中心,国家药品监督管理局化妆品安全评价重点实验室,广东 广州 510515
- Keywords:
alternative toxicity testing methods;
health risk assessment;
cosmetics;
new approach methodologies
- From:
Chinese Journal of Pharmacology and Toxicology
2024;38(10):723-733
- CountryChina
- Language:Chinese
-
Abstract:
With the rapid development of industry and economy,the emergence of a large number of chemicals has made of risk management more difficult.Traditional risk assessment relies on animal experiments for toxicity testing.However,animal experiments are time-consuming,costly,and unable to meet the practical needs of risk assessment.The increasing maturity of toxicity testing alternative technologies signifies the possibility of rapid,sensitive,and accurate identification of chemical toxicity.This article focuses on the research and applications of alternative toxicity testing by reviewing the background,developments,and current research at home and abroad.It also discusses the progress in alternative testing methods in such areas as cosmetics and food safety risk assessment and explores the problems with the development of alternative testing technologies and risk assessment in China.This review aims to provide a reference for the system construction of cosmetics health risk assess-ment in China.
