New advances in pharmacological effects and mechanisms of ganoderic acid A
10.3867/j.issn.1000-3002.2024.08.007
- VernacularTitle:灵芝酸A药理作用及其机制研究新进展
- Author:
Zhen XIE
1
;
Kang YE
;
Rong KUANG
;
Jingxian LU
;
Bilian CHEN
Author Information
1. 浙江省食品药品检验研究院 国家药品监督管理局化妆品动物替代试验技术重点实验室,浙江杭州 310052
- Keywords:
ganoderic acid A;
pharmacodynamics;
pharmacokinetics
- From:
Chinese Journal of Pharmacology and Toxicology
2024;38(8):619-632
- CountryChina
- Language:Chinese
-
Abstract:
Ganoderma lucidum is one of the widely-used traditional Chinese medicines.Ganoderma lucidum extract and Ganoderma spore powder are also widely used in foods,health care and cosmetics,and are highly favored by consumers.Ganoderic acid A is one of the main effective components of Ganoderma lucidum triterpenoids.In recent years,a large number of studies have proved that ganoderic acid A has anti-tumor,anti-inflammatory,hepatoprotection,hypolipidemic,renoprotective properties,and has therapeutic potential in psychiatric and neurological disorders.,which has high medicinal value and good prospects for development.Based on review of domestic and foreign literatures in recent years,the new research progress in pharmacology of ganoderic acid A is summarized in this paper in order to provide references for its further development and clinical applications.
