Research progress in roles of macrophage-capping protein in tumor invasion and metastasis
10.3867/j.issn.1000-3002.2024.07.008
- VernacularTitle:巨噬细胞加帽蛋白在肿瘤侵袭和转移中的作用研究进展
- Author:
Xia CUI
1
,
2
;
Zhiyong XIAO
;
Feng LIU
;
Wenxia ZHOU
Author Information
1. 军事医学研究院国家安全特需药品全国重点实验室,北京 100850
2. 南京中医药大学,江苏南京 210023
- Keywords:
macrophage-capping protein;
structure;
function;
signal path;
tumor invasiveness
- From:
Chinese Journal of Pharmacology and Toxicology
2024;38(7):542-549
- CountryChina
- Language:Chinese
-
Abstract:
Macrophage-capping protein(CapG)is a member of the gelsolin superfamily.It is a universal multifunctional actin binding protein in the body and highly expressed in breast cancer,bladder cancer,prostate cancer and other types of cancer,which can promote the metastasis and invasion of cancer cells.This article reviews the structure,function,related signal pathways and roles of CapG in tumor invasiveness.
