Research progress on neuroinflammation-related biomarkers in cognitive impairment diseases
- VernacularTitle:认知障碍疾病神经炎症相关生物标记物研究进展
- Author:
Xiao-Yu SONG
1
,
2
;
Jie ZHANG
;
Xu WANG
;
Jian-Ping DUAN
;
Jin-Beng DING
Author Information
- Keywords: cognitive impairment; neuroinflammation; astro-cytes; microglia; regulatory mechanism; inflammatory factor
- From: Chinese Pharmacological Bulletin 2024;40(12):2218-2223
- CountryChina
- Language:Chinese
- Abstract: Diagnosis and treatment of cognitive impairment is one of the difficult problems in the diagnosis and treatment of brain diseases.Any factor that causes functional and structural abnormalities in cerebral cortex can lead to cognitive impair-ment,which has a high incidence,a large number of patients and a heavy burden of disease.Because of the complexity of its pathogenesis,no effective preventive and curative measures have yet been taken.In recent years,many studies reveal that neu-roinflammation is involved in the pathogenesis of neurological diseases related to cognitive impairment,which has become a re-search hotspot in this field.This article provides a summary of the role of neuroinflammation-related biomarkers in the patho-genesis of cognitive impairment and their regulatory mecha-nisms,with a view to providing a further theoretical basis for the prevention and treatment of cognitive impairment.
