Mixed or Combined IgA Nephropathy and Membranous Glomerulonephritis.
- Author:
Hyun Ee YIM
1
;
Sun Won HONG
;
Do Hun KIM
Author Information
1. Department of Pathology, Wonju College of Medicine Yonsei University, Korea.
- Publication Type:Case Report
- Keywords:
IgA nephropathy;
Membranous glomerulonephritis
- MeSH:
Capillaries;
Fluorescent Antibody Technique, Direct;
Glomerulonephritis, IGA*;
Glomerulonephritis, Membranous*;
Hepatitis B Surface Antigens;
Humans;
Immunoglobulin A*;
Immunoglobulin G;
Mesangial Cells;
Microscopy, Electron;
Middle Aged;
Nephrotic Syndrome
- From:Korean Journal of Nephrology
1997;16(2):365-368
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a rare case of primary glomerular disease with both features of IgA nephropathy and membranous glomerulonephritis in a 45 year-old, HBsAg negative man with nephrotic syndrome. Histologically, glomeruli showed mesangial expansion, proliferation of mesangial cells, and diffuse thickening of capillary walls. Direct immunofluorescence demonstrated granular IgG and C3 deposits along the capillary walls and IgA deposits in mesangiums. Granular subepithelial and mesangial depoists were observed by electron microscopy.