Research progress on mechanism of interaction between traditional Chinese medicine and intestinal flora
10.12360/CPB202211010
- VernacularTitle:中药与肠道菌群相互作用机制研究进展
- Author:
Jing WU
1
;
Wei-Yi TIAN
;
Kun CAI
;
Su-Fang ZHOU
;
Yao-Feng LI
;
Xiang-Yun CHEN
;
Hai-Bing QIAN
;
Sha-Sha YANG
Author Information
1. 贵州中医药大学基础医学院
- Keywords:
traditional Chinese medicine;
gut microbiota;
inter-play;
active ingredients;
metabolism;
molecular mechanisms
- From:
Chinese Pharmacological Bulletin
2024;40(10):1823-1829
- CountryChina
- Language:Chinese
-
Abstract:
Modern Chinese medicine studies have confirmed that the interaction between traditional Chinese medicine(TCM)and intestinal flora is the key to the treatment of diseases with tradi-tional Chinese medicine.This interplay includes such activities as:traditional Chinese medicine can be metabolized by intestinal flora into effective components with different biological activities from its precursors;TCM chemicals improve the composition of gut microbiota,consequently ameliorating its dysfunction as well as associated pathological conditions;and gut microbiota mediate the interactions between the multiple chemicals in TCM.There-fore,it becomes an important way to understand the modern sci-entific connotation of traditional Chinese medicine theory to study the pharmacological mechanism of the efficacy of traditional Chi-nese medicine by targeting Gut microbiota.
