Analysis of factors influencing clinical outcomes in the first frozen-thawed embryo transfer cycles
10.12007/j.issn.0258-4646.2024.09.005
- VernacularTitle:首次冻融胚胎移植周期临床结局的影响因素
- Author:
Kaixuan SUN
1
;
Yinling XIU
;
Yinghua WANG
;
Yitong ZHANG
;
Xiaoli LU
;
Jing ZHOU
;
Yuexin YU
Author Information
1. 中国人民解放军北部战区总医院生殖医学科,沈阳 110003
- Keywords:
assisted reproductive technology;
frozen-thawed embryo transfer;
clinical pregnancy rate;
live birth rate
- From:
Journal of China Medical University
2024;53(9):793-797
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the influencing factors of clinical pregnancy and live birth rates in patients undergoing frozen-thawed embryo transfer(FET)for the first time.Methods The clinical data of 1 458 patients who underwent FET cycle-assisted pregnancy for the first time were retrospectively analyzed and divided into four groups according to clinical pregnancy and live bith outcomes.The clini-cal data were compared to analyze the factors affecting clinical pregnancy and live birth rates in FET cycles that were included in multiple logistic regression analysis.Results Of the 1458 cycles,the clinical pregnancy and live birth rates were 44.0% and 34.0%,respectively.The mean age of the clinical pregnancy and live birth groups was lower than that in non-clinical pregnancy and stillbirth groups(P<0.05).The clinical pregnancy and live birth rates of patients aged<35 years were higher than those aged≥35 years(P<0.05).The clinical preg-nancy and live birth rates of patients with≥8 mm endometrial thickness were higher than those with<8 mm endometrial thickness(P<0.05).The clinical pregnancy rate of natural cycles of endometrial preparation regimen was higher than that of HRT cycles(P<0.05).The clinical pregnancy and live birth rates of double-embryo transfers were higher than that of single-embryo transfers(P<0.05).The clinical pregnancy and live birth rates of blastocyst transfers were higher than those of cleavage stage(P<0.05).Conclusion Age,endometrial thickness,number of transplanted embryos,and embryo morphology were the independent factors influencing clinical pregnancy and live birth outcomes during FET cycle transplantation.
