Distribution of Rotavirus G Serotypes in ChungJu Area.
- Author:
Jae Geon SIM
1
;
Jae Bong KWON
;
Shien Young KANG
Author Information
1. Department of Pediatrics, Kon-Kok University Hospital, Chungiu, Korea. psychild@kku.edu
- Publication Type:Original Article
- Keywords:
Rotavirus;
Serotype G;
VP7
- MeSH:
Child;
Chungcheongbuk-do*;
Humans;
Incidence;
Korea;
Rotavirus Vaccines;
Rotavirus*
- From:Korean Journal of Pediatric Gastroenterology and Nutrition
2000;3(1):41-46
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: It is important to have the epidemiologic data of rotavirus serotypes for the application of polyvalent rotavirus vaccines. Epidemiological studies of rotavirus serotypes in Korea have been reported only in limited areas with small number of cases. Authors tried to investigate the distribution of rotavirus G serotypes in ChungJu area with RT-PCR. METHOD: Stool specimens were collected from 202 children with acute diarrheal symptoms, who admitted to or visited Kon-Kuk University Hospital in ChungJu from June 1998 to May 1999. Samples were screened for rotavirus with EIA method (TestPack Rotavirus, Abbott Laboratories) and rotavirus G Serotypes were determined by RT-PCR. RESULTS: Rotavirus was positive in 46.6%. The incidence of G serotypes was as follows; G1 10%, G2 10%, G3 28%, G4 26%, and G9 20%. There were three cases of multiple serotypes; G1 with G9, G2 with G9, and G4 with G9. Serotype of G8 was not found. CONCLUSION: The proportion of G serotypes in ChungJu is much different from previous reports. Serotype of G9 was found which had not been reported in Korean children till now. Long term plans for the investigation of rotavirus serotypes must be needed in wide area.
