Muscle-brain crosstalk mechanisms in the cognitive-motor interference effects of freezing of gait in Parkinson disease
10.3760/cma.j.cn371468-20240317-00115
- VernacularTitle:帕金森病冻结步态认知-运动干扰效应中的肌-脑串扰机制
- Author:
Pei LI
1
;
Peizhu ZHANG
;
Gongqiang WANG
;
Xinfeng MA
;
Guang'an TONG
;
Kang LIN
;
Ping JIN
Author Information
1. 安徽中医药大学研究生院，合肥 230012
- Keywords:
Parkinson disease;
Freezing of gait;
Cognitive-motor interference;
Dual tasks;
Myokine
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2024;33(9):813-818
- CountryChina
- Language:Chinese
-
Abstract:
Freezing of gait is a common gait disorder in Parkinson disease (PD), which is highly disabling, situational and therapeutically challenging. At present, there is no clear and effective intervention method. In recent ten years, exercise training based on cognitive-motor dual tasks has been more and more used in the intervention treatment of freezing of gait of PD patients, and achieved certain clinical results. The muscle-brain crosstalk effect of exercise training promoting muscle secretory factors is crucial for freezing of gait rehabilitation of PD. There are differences in the effects of cognitive-motor dual tasks of different types and loads on gait, but the specific training types and loads and mechanism of action still need to be further elucidated. This paper focuses on the research progress of muscle-brain crosstalk mechanism in cognitive-motor interference effect of freezing of gait in PD patients, aiming to providing a new theoretical perspective for clinical cognitive-motor training intervention of freezing of gait in PD patients.
