Research progress on transcranial alternating current stimulation for regulating neural oscillations in Parkinson disease

VernacularTitle:经颅交流电刺激调控帕金森病神经振荡的研究进展
Author: Xiaoyu LIAO ¹ ; Yan GONG ; Aisong GUO
Author Information

1. 南通大学医学院，南通　226001
Keywords: Parkinson disease; Biomarkers; Transcranial alternating current stimulation; Neural modulation; Neural oscillations
From: Chinese Journal of Behavioral Medicine and Brain Science 2024;33(7):660-664
CountryChina
Language:Chinese
Abstract: Parkinson disease (PD) is a neurodegenerative disorder of unknown cause. Its onset and progression are closely linked to abnormal neural oscillations, which are one of the biomarkers used to assess PD. Current research focuses on exploring the relationship between neural oscillations and PD and targeting abnormal neural oscillations in PD patients. Transcranial alternating current stimulation (tACS) is an emerging non-invasive brain stimulation technique that influences neural activity in the brain by applying biphasic and sinusoidal currents and has shown potential in modulating abnormal neural oscillations in PD. This paper reviews the neural oscillations commonly found in PD, the mechanisms by which tACS regulates PD-related neural oscillations, and the current progress in tACS application for PD. It also discusses the challenges and future trends in the field, with the aim of providing new insights for the treatment and clinical research of PD.