Event-related potential study on vigilant attention in children with sleep disordered breathing
10.3760/cma.j.cn371468-20231008-00150
- VernacularTitle:睡眠呼吸障碍儿童警觉性注意的事件相关电位研究
- Author:
Ye HE
1
;
Huijie HAN
;
Ming FA
;
Chaoqun WANG
;
Haitian MEI
;
Fangqiao ZHAO
;
Yang YI
Author Information
1. 南通大学附属常州儿童医院呼吸科，常州 213000
- Keywords:
Sleep disordered breathing;
Event-related potential;
School-age children;
Vigilant attention;
Contingent negative variation
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2024;33(6):500-504
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the vigilant attention function and behavioral changes in sleep disordered breathing(SDB) children.Methods:Thirty SDB children (SDB group) and 30 normal children (control group) were selected from June 2022 to August 2023. All participants underwent continuous performance test(CPT-AX) (Go/Nogo) and behavioral test. The latency and amplitude of contingent negative variation(CNV) components under cue/uncue conditions in leads F3, Fz and F4 were measured. The t-test and Mann-Whitney U test were used to conduct statistical analysis by SPSS 25.0 software. Results:(1) There were no statistically significant differences in the number of correct responses, reaction time and number of false alarms between the SDB group and the control group (all P>0.05).(2) The latencies of cue-CNV in the SDB group(F3: 618.00(582.50, 644.50)ms, Fz: 603.00(579.50, 634.00)ms, F4: (606.87±25.07)ms) were longer than those in the control group(F3: (508.47±25.82)ms, Fz: 502.00(470.00, 520.50)ms, F4: 514.00(487.00, 536.50)ms) in leads F3, Fz and F4. The latency of cue-CNV of lead F4 in the SDB group was higher than that in the control group, and the difference was statistically significant ( P<0.05). The latencies of uncue-CNV in lead F3 and Fz in the SDB group were higher than those in the control group, and the differences were statistically significant (both P<0.05). Conclusion:SDB children have shown activation in the right brain area during attentional tasks, and the prolonged CNV latency may be a sensitive neuroelectrophysiological marker for early clinical assessment of vigilant attention dysfunction.
