A meta-analysis of effects of combined cognitive intervention and physical intervention on mild cognitive impairment
10.3969/j.issn.1000-6729.2024.07.007
- VernacularTitle:认知干预联合运动干预对轻度认知障碍效果的meta分析
- Author:
Guangwen LIU
1
;
Chenlu HONG
;
Takching TAI
;
Zhaorui LIU
;
Yanan LUO
Author Information
1. 北京大学公共卫生学院全球卫生学系,北京 100191
- Keywords:
cognitive intervention;
physical intervention;
combined intervention;
mild cognitive impair-ment;
meta-analysis
- From:
Chinese Mental Health Journal
2024;38(7):591-598
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effect of combined cognitive and physical intervention on mild cogni-tive impairment(MCI)using meta-analysis.Methods:Five databases including CNKI,PubMed,Web of Science,Cochrane and Embase were retrieved.Randomized Control Trials containing the combined cognitive and physical therapies on MCI were included.Statistical analysis,including the evaluation of the effects on global cognition,memory and executive function or attention,as well as the subgroup analysis were conducted using Stata 15.0.Results:A total of 28 articles was eventually included,with 2 796 participants.Results showed that the effec-tiveness of combined intervention on global cognitive function(SMD=0.68,95％CI:0.39-0.97),memory(SMD=0.35,95％CI:0.01-0.68)as well as executive function or attention(SMD=-0.28,95％CI:-0.51--0.05)were significantly better than the control group.Subgroup analysis indicated that the effects of combined intervention on the above domains of cognitive function among the participants were affected by the intervention mode,control type,whether there were other interventions and intervention frequency.Conclusion:Combined cogni-tive and physical intervention could effectively improve mild cognitive impairment.
