Relation of self-injury behavior to thyroid hormones and lipids in adolescent patients with depression
10.3969/j.issn.1000-6729.2024.05.010
- VernacularTitle:青少年抑郁症患者自伤行为与甲状腺激素和脂类的关系
- Author:
Min WEN
1
,
2
;
Yunshu ZHANG
;
Jinning LIU
;
Jinyun HU
;
Xinwei ZHANG
;
Lili ZHANG
;
Bing LI
;
Keqing LI
Author Information
1. 华北理工大学,河北唐山 063000
2. 河北省精神卫生中心,河北省重大精神与行为疾病重点实验室,河北保定 071000
- Keywords:
self-injury;
depression;
adolescents;
thyroid hormones;
lipids
- From:
Chinese Mental Health Journal
2024;38(5):433-438
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the relation of self-injury behavior to thyroid hormones and lipids in adoles-cent patients with depression.Methods:A total of 182 adolescent inpatients who met the diagnostic criteria for de-pression according to the Diagnostic and Statistical Manual of Mental Disorders,Fifth Edition(DSM-5)were en-rolled,including 38 cases with self-injurious behavior and 144 cases without self-injurious.The differences in vari-ous indicators between the two groups were compared,and logistic regression analysis was used to analyze factors related to self-injury in adolescents with depression.Results:The patients with self-injurious behavior had higher levels of total cholesterol and high-density lipoprotein cholesterol(HDL-C)compared to those without self-injuri-ous behavior(P＜0.05).They also had lower levels of free thyroxine compared to the group without self-injurious behavior(P＜0.05).Logistic regression analysis results showed that those with longer duration of disease(OR=1.03)and higher HDL-C levels(OR=12.75)were more likely to have self-injurious behaviors.Conclusion:Long duration of disease and high level of HDL-C may be risk factors for self-injurious behavior in adolescents with de-pression,while low level of free thyroxine may serve as a protective factor.
