Clinical Characteristics,Management,and One-year Outcome of Patients Hospitalized for Acute Heart Failure in Different Regions of China
10.3969/j.issn.1000-3614.2024.06.010
- VernacularTitle:我国不同地区急性心力衰竭住院患者的临床特征、诊疗情况及预后差异
- Author:
Huanmei LIU
1
;
Lihua ZHANG
Author Information
1. 中国医学科学院 北京协和医学院 国家心血管病中心 阜外医院 国家心血管疾病临床医学研究中心,北京 100037
- Keywords:
heart failure;
clinical characteristics;
outcome;
regional difference
- From:
Chinese Circulation Journal
2024;39(6):592-598
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To analyze the differences in clinical characteristics,in-hospital management and one-year outcome of patients hospitalized for acute heart failure in the eastern,central,and western regions of China. Methods:Data was obtained from the China Patient-centered Evaluative Assessment of Cardiac Events(PEACE)-Prospective Heart Failure Study.A total of 4 875 patients aged 18 and above hospitalized for acute heart failure were enrolled from 52 hospitals in China between August 2016 and May 2018.Patients were categorized into three groups according to their geographical locations:eastern(n=1 753),central(n=1 723),and western(n=1 399).The clinical characteristics,in-hospital management,and one-year outcome were compared among the three groups. Results:The included patients had a median age of 67(57,75)years,of whom 37.5%were women.In all patients,the main comorbidities of heart failure included hypertension(56.0%),coronary heart disease(52.1%),atrial fibrillation(34.3%),and chronic kidney disease(34.3%).The proportion of patients with hypertension in the western region(60.3%)was higher than that in the eastern(53.9%)and central regions(54.7%,both P<0.017).The proportions of beta blockers,mineralocorticoid receptor antagonist,and diuretic use during hospitalization in the central region were 67.3%,79.9%and 85.2%,respectively,significantly lower than those in the eastern(79.3%,86.3%and 89.6%)and western(75.3%,83.6%and 89.1%)regions(all P<0.017).Arter adjusted for age and sex,there was no statistical difference in all-cause mortality among the three groups during one-year follow-up after discharge,while the risk of cardiovascular mortality in the eastern region was significantly higher than that in the western region within one year after discharge(HR=1.33,95%CI:1.07-1.65,P<0.017). Conclusions:Present results indicate that the clinical characteristics and in-hospital management of patients hospitalized for acute heart failure differ among the eastern,central,and western regions of China.The risk of cardiovascular mortality in the eastern region is higher than that in the western region during one-year follow-up after discharge.
