Effect of arctiin on hemorheology of experimental rats with blood stasis ayndrone
10.3969/j.issn.1007-7693.2006.06.005
- VernacularTitle:牛蒡子苷对血瘀大鼠血液流变学的影响
- Author:
Yi-Min ZHENG
1
;
Xiu-Ying XU
;
Shao-Xi CAI
;
Shan-Quan FU
Author Information
1. 重庆工学院
- Keywords:
Arctium lappa L;
arctiin;
hemorheology;
anti-coagulation
- From:
Chinese Journal of Modern Applied Pharmacy
2006;23(6):443-446
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study influence of arctiin from seeds of Arctium lappa on hemorheology of experimental rats with the blood stasis syndrone. METHODS The blood hemorheology parameters, Fib, aPTT and PT of experimental rats with the blood stasis syndrone were evaluated using semi-automatic biochemical analysis. RESULTS Arctiin obviously decreased their high shear, middle shear, low shear, the blood viscosity, red blood cell aggregation index, red blood cell rigidity index and reductive viscosity. It also significantly prolonged the time of aPTT and PT and lowed the Fib concentration. CONCLUSION Arctiin apparently ameliorated the blood rheology abnormality and enhanced anti-coagulation effect on experimental rats with the blood stasis.