Flavonol and monoterpene glycosides from Ligularia macrophylla
10.3969/j.issn.1007-7693.2005.03.001
- VernacularTitle:大叶橐吾中的黄酮醇苷和单萜苷
- Author:
Yun-Xue PAN
1
;
Hui DOU
;
Xiao-Xiang ZHENG
;
Xiao-Zhong GAO
;
Chang-Xin ZHOU
;
Yu ZHAO
Author Information
1. 浙江大学
- Keywords:
Ligularia macrophylla;
compositae;
flavonol glycosides;
monoterpene glycosides
- From:
Chinese Journal of Modern Applied Pharmacy
2005;22(3):175-178
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the chemical constituents of the roots and rhizomes of Ligularia macrophylla.METHODS The compounds were isolated through repeated column chromatography on silica gel, polyamide, RP-18 and Sephadex LH-20. And the structures were elucidated on the basis of spectroscopic data (UV, IR, MS, 1H NMR, 13C NMR, DEPT and 2D NMR). RESULTS Four flavonol glycosides and two monoterpene glycosides were obtained and determined as rhamnazin-3-O-β-D-rutinoside ( 1 ), rhamnetin-3-O-β-D-rutinoside ( 2), rutin ( 3), afzelin ( 4), betulalbuside A (5) and 3,7-dimethyloct-1 -en-3,8-diol8-O-β-D- glucopyranoside (6). CONCLUSION All the compounds were isolated from this plant for the first time.
