Detetmination of two components in antiasthmatic mixture by derivative spectrophotomety
10.3969/j.issn.1007-7693.2001.02.026
- VernacularTitle:导数光谱法测定抗喘合剂中两组分含量
- Author:
Xuefeng CHEN
1
Author Information
1. The fitst Hospital of Huzhou
- From:
Chinese Journal of Modern Applied Pharmacy
2001;18(2):134-136
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To detetmine oinultaneous ly ephedtine hydrochlotide and diphenhydtamine hydtochlotiae without any sepatat ion in Antiasthmatic Mixtute.METHOD:Double-Wavelelength secondaty d erivative spectrophotometry and secondary derivative spectrophotometry were used .RESULTS:The content of ephedrine hydrochloride and diphenhydramine hydrochloride could be obtained respectively Linear ranges were both 5.0~25μg/ ml,the correlation coefficients were 0.9994 and 0.996,the average recoveries wer e 99.7% and 96.6%,RSD were 0.6% and 0.4%,respectively.CONCLUSION:The method was simple,rapid and accurate for routine analysis of hospital preparat in.