Determination of bleonycinA5 cream by ultraviolet spectrophotom etry
10.3969/j.issn.1007-7693.2001.02.018
- VernacularTitle:紫外分光光度法测定平阳霉素霜的含量
- Author:
Jun YAN
1
;
Junren ZHANG
;
Haina WANG
Author Information
1. Jinan City Hospital for Shin Diseases Prevention
- From:
Chinese Journal of Modern Applied Pharmacy
2001;18(2):119-120
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To determine bleomycinA5 cream and provide a methods for quality control.METHODS:Ultraviolet spectrophotometry was used.RESULTS:The maxium absorption of bleonyc inA5 in methanol is 293.5nm.The absorbance was linear with concentration of bl eomycinA5 within the range of 30~70μg/ml.Its regression equation is A =0.01066C-0.008(r=0.99998).The average recovery of bleomycinA5 was 100.0 5%,RSD=0.98%(n=5).CONCLUSION:The method is s imple,quick and accurate for simultaneous determination of bleomycinA5 cream.