Synthesis of Etifenin
10.3969/j.issn.1007-7693.2001.02.016
- VernacularTitle:依替菲宁的合成
- Author:
Gaolin LIANG
1
;
Mingyang HU
;
Yanhua YU
Author Information
1. Jiangsu Institute of Nuclear Medicine
- From:
Chinese Journal of Modern Applied Pharmacy
2001;18(2):117-118
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To synthesize N-(2, 6-Diethylphenylcarbamoylmethyl) iminodiacetic acid(Etifenin),a precursor of hepa to-biliary imaging agent.METHOD:Target molecular was synthesized fro m 2,6-diethylaniline,with the improved processes.Chemical structures of products were confirmed by IR,1HNMR,and 13CNMR.RESULTS:This syn thetic route is simpler,the yield is higher than those of documents reported.CONCLUSION:This synthetic route is practical.
