The stable factors on nimodipine injection
10.3969/j.issn.1007-7693.2001.02.011
- VernacularTitle:国产尼莫地平注射液稳定性影响因素试验
- Author:
Suiqing HE
1
;
Xinjian SHI
;
Jian HUANG
Author Information
1. zhejiang Yinxin pharmaceutical Co.Ltd
- From:
Chinese Journal of Modern Applied Pharmacy
2001;18(2):107-109
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE：To invesitigate efects of temperature and light on content and the related substances Nimodipine lnject ion.METHODS:Put them into different conditions(4℃,40℃,60℃,80℃,st rong light of 3000Ix,nature light),detemine its content and related substances b y HPLC.RESULTS:on the condition of strong light,the Nimodipine lnjec tion is not stable.After 5,10,24 hours,the content becomes 96.6%,69.5%,40.2% res pectively and the related substances.increase,but on other conditions,it is rath er stable.CONCLUSION:It should be avoided strong light when store an d use.
