Metabolism of natural products by intestinal bacteria
10.3969/j.issn.1007-7693.2001.02.002
- VernacularTitle:肠道细菌对天然药物代谢的研究进展Ⅰ
- Author:
Mingjie LIU
1
;
Lin LIN
;
Zhao WANG
Author Information
1. 清华大学
- From:
Chinese Journal of Modern Applied Pharmacy
2001;18(2):90-91
- CountryChina
- Language:Chinese
-
Abstract:
To review the progress in the metablism of natural products by intestinal bacteria.METHOD: According to the recent literatures on this subject,the metablism of flavonoids, saponins,lignans,iridoid glucosides,etc,was summarized and evaluated.RESUL TS:Natural products can be biotransformed into some new compounds by intes tinal bacteria,which may have pharmacological or toxicological activities. CONCLUSION:Many natural products may be metabolized in vivo and are called prodrugs.The intestinal bacteria may be of great significance in determining th e metabolic fate of natural drugs.