Efficacy observations of repaglinide in the treatment of type 2 diabetes among 68 cases
10.3969/j.issn.1007-7693.2000.03.030
- VernacularTitle:瑞格列奈治疗2型糖尿病68例疗效观察
- Author:
Shuchang LU
1
;
Zhaode ZHU
;
Jianjin SHEN
;
Xiaodong DU
Author Information
1. Hangzhou Municipal Red-Cross Hospital
- Keywords:
type 2 diabetes;
repaglinide
- From:
Chinese Journal of Modern Applied Pharmacy
2000;17(3):237-238
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the therapeu tic effectiveness of repaglinide in lowering the FBG and PPBG in type 2 diabetes among 68 patients.METHODS:68 cases were divided at random into two groups:Repaglinide group(34 patients, 17female, 17male) and Placebo-controlled gr oup(34 patients,16female and 18male).0.5mg repaglinide was taken orally before e ach meal in therapeutic group for 4 weeks,while the cases in control were treate d by placebo.RESULTS:Repaglinide could effectively decrease the leve ls of FBG,PPBG and HbA1C with significant difference when compare with the place bo(P<0.01).At the meantime,it could also lower the Cholesterol and triglyceride levels when compared with the control group(P<0.01).CO NCLUSION:Repaglinide was effective in lowering the levels of FBG,PPBG and HbA1C in type 2 diabetes patients without obvious side effects.