A clinical study of ultrasound-guided percutaneous thermal ablation for multiple T1N0M0 papillary thyroid carcinoma with over 5 years follow-up
10.3969/j.issn.1009-9905.2024.07.008
- VernacularTitle:超声引导热消融治疗多灶性T1N0M0甲状腺乳头状癌5年以上随访的临床研究
- Author:
Hao SUN
1
;
Yan WANG
;
Yi MAO
;
Chao ZHANG
;
Guo-Zheng ZHAO
;
Guan-Li HAN
;
Ming-Bo ZHANG
Author Information
1. 中国人民解放军总医院第一医学中心 超声诊断科(北京 100853)
- Keywords:
Ultrasound;
Thermal ablation;
Papillary thyroid carcinoma;
Outcome
- From:
Chinese Journal of Current Advances in General Surgery
2024;27(7):543-548
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the safety and efficacy of ultrasound-guided percutaneous thermal ablation treatment for multiple T1N0M0 papillary thyroid carcinoma(PTC)with over 5 years follow-up.Methods:From January 2014 to January 2019,a retrospective analysis was conducted on patients with multiple T1N0M0 PTC who underwent ultrasound-guided thermal ablation.Patients with bilateral or unilateral lobes with isthmus PTC were enrolled in this study and were followed up at 1,3,6,12,24,36,48,and 60 months after ablation.The clinical data,ultrasound characteristics and ablation parameters of recurrent and non-recurrent patients were compared,and the efficacy and influencing factors of thermal ablation for multiple T1N0M0 PTC were analyzed.Results:After over 5 years follow-up,a total of 11 patients(16.18％)relapsed,57 patients(83.82％)did not re-lapse.No lymph node and distant metastasis were found.No significant correlation was detected between the recurrence and clinical features,ultrasound findings and ablation parameters(P＞0.05).Among the patients with recurrence,1 patient underwent observation,2 patients underwent total thyroidectomy,and the other 8 patients successfully underwent secondary ablation,all of which had no obvious adverse reactions.Conclusion:The ablation of multiple PTC in T1N0M0 stage is safe and effective,with a recurrence rate of 16.18％over 5 years follow-up,and ablation has no effect on second treatment for recurrent patients.
