Myelodysplastic Syndrome in a Renal Transplant Recipient Treated with Long-term Azathioprine.
- Author:
Hyuk Sang KWON
1
;
Sung No YOON
;
Chul Woo YANG
;
Seung Hun LEE
;
Yong Soo KIM
;
Suk Young KIM
;
Euy Jin CHOI
;
Byung Kee BANG
Author Information
1. Department of Internal Medicine, Catholic University Medical College, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Myelodysplastic syndrome;
Renal transplantation;
Azathioprine
- MeSH:
Adult;
Azathioprine*;
Biopsy;
Blood Platelets;
Bone Marrow;
Hematocrit;
Humans;
Kidney Transplantation;
Myelodysplastic Syndromes*;
Pancytopenia;
Transplantation*
- From:Korean Journal of Nephrology
1997;16(2):412-416
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 39-year-old renal transplant recipient was admitted for evaluation of pancytopenia which developed gradually 10 months ago. He received renal transplantation 10 years ago and maintained relatively good renal function. Since 1 year before admission, he showed progressive decline of hematocrit, WBC count and platelet. Initial bone marrow biopsy showed erythroid hypoplasia, and second bone marrow biopsy revealed myelodysplasia. Clinical course was fatal. In conclusion, if patients with long term azathioprine treatment show progressive pancytopenia, one should suspect the possibility of myelodysplastic syndrome.
