Effect of early glucose metabolism abnormality on skeletal muscle content of young men
10.3969/j.issn.1006-6187.2024.10.006
- VernacularTitle:早期糖代谢异常对青年男性骨骼肌含量影响的研究
- Author:
Dongmei FAN
1
;
Guangfei WU
;
Xing WANG
;
Junru LIU
;
Bowei LIU
;
Fuzai YIN
Author Information
1. 066000 秦皇岛市第一医院内分泌科
- Keywords:
Glucose metabolism abnormality;
Young men;
Skeletal muscle content;
Body fat ratio
- From:
Chinese Journal of Diabetes
2024;32(10):746-749
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of early glucose metabolism abnormality on skeletal muscle content of young men.Methods 88 males who underwent physical examinations in our hospital from September 2020 to September 2021 were divided into normal blood glucose group(NGT,n=47)and IGR group(n=41),according to their FPG and 2 hPG levels.FPG,FIns and visceral fat area(VFA)were measured.HOMA-IR,HOMA-β,skeletal muscle index(SMI)and body fat ratio(BFR)were calculated.Results Compared with NGT group,the males in IGR group showed elevated BMI,WC,FPG,2 hPG,HOMA-IR and VFA(P＜0.05),but decreased HDL-C and SMI(P＜0.05).Pearson correlation analysis showed that SMI was negatively correlated with BMI,WC,FPG,2 hPG,HOMA-IR,VFA and BFR in young men(P＜0.05 or P＜0.01).Logistic regression analysis showed that BMI was the influencing factor of FPG,while SMI was the influencing factor of 2 hPG.Conclusions In young men with abnormal glucose metabolism,the postprandial blood glucose significantly increase with the decrease of skeletal muscle content,and fasting blood glucose is mainly affected by BMI.
