Research progress of the mTOR signaling pathway in diabetic retinopathy
10.3969/j.issn.1006-6187.2024.06.016
- VernacularTitle:哺乳动物雷帕霉素靶蛋白信号通路在糖尿病视网膜病变中作用的研究进展
- Author:
Zhaohua XU
1
;
Jianping SHI
Author Information
1. 010000 呼和浩特,内蒙古医科大学中医学院
- Keywords:
Diabetic retinopathy;
Mammalian;
Target of rapamycin;
Signaling pathway;
Oxidative stress;
Autophagy
- From:
Chinese Journal of Diabetes
2024;32(6):478-480
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic retinopathy(DR)is a microvascular lesion in diabetes mellitus(DM),which is the main cause of irreversible blindness.The prevalence of DR increases as the number of DM patients increases.Due to limited treatment options,the overall cure rate is low.Mammalian target of rapamycin(mTOR)plays an important role in the occurrence and development of diabetic retinopathy as a hyperglycemic sensor.This article reviews the research progress on the role of mTOR signaling pathway in DR.
