Research Advances of Exosomes in Pathogenesis of Multiple Myeloma——Review
10.19746/j.cnki.issn1009-2137.2024.05.048
- VernacularTitle:外泌体在多发性骨髓瘤发病机制中的研究进展
- Author:
Xin-Yue LANG
1
;
Qiu-Rong ZHANG
;
Jin-Ge XU
Author Information
1. 徐州医科大学第二附属医院血液科,江苏徐州 221006
- Keywords:
multiple myeloma;
exosome;
bone marrow microenvironment
- From:
Journal of Experimental Hematology
2024;32(5):1614-1617
- CountryChina
- Language:Chinese
-
Abstract:
Research on the participation of exosomes in pathogenesis and prognosis of multiple myeloma(MM)has made encouraging progress.However,the specific mechanism has not yet been clarified.Recently,domestic and foreign researchers have pressed forward on deeper study on exosomes.This article mainly summarizes the role of exosomes in the pathophysiological processes,such as bone marrow microenvironment changes,immunosuppression,myeloma bone disease generation and myeloma drug resistance,so as to provide new reference for further clinical research of exosomes as potential biomarkers for MM.
