Correlation Analysis of the Number of Hemophagocytes and Peripheral Blood Cells in Bone Marrow
10.19746/j.cnki.issn1009-2137.2024.01.043
- VernacularTitle:骨髓中噬血细胞数量与外周血细胞数量的相关性分析
- Author:
Meng-Ting MA
1
;
Wan-Lin TIAN
;
Nan WU
;
Qiang ZHANG
;
Feng-Chao WANG
Author Information
1. 蚌埠医学院第一附属医院检验科,安徽蚌埠 233000
- Keywords:
fever;
hemophagocytes;
bone marrow cytology;
missing rate
- From:
Journal of Experimental Hematology
2024;32(1):269-273
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the correlation between the number of hemophagocytes and peripheral blood cells in bone marrow of patients with fever of unknown origin.Methods:A total of 465 patients with fever of unknown origin in our hospital from January 2019 to December 2021 were selected as the research objects,which was to reviewed retrospectively the correlation between the number of hemophagocytes and peripheral blood cells in bone marrow.Results:The positive rates of hemophagocytes detected in the three lines decreased group,the two lines decreased group,the one line decreased group,normal group of the three lines and at least one of the three lines increased group were 86.4％,62.1％,38.3％,34.6％and 33.3％,respectively.The number of hemophagocytes per unit area in the three lines decreased group was significantly higher than that in the other four groups(P＜0.001).The number of hemophagocytes per unit area in the two lines decreased group was higher than that in the one line decreased group,normal group of three lines and at least one of the three lines increased group(P＜0.01).There was no significant difference in the number of hemophagocytes per unit area between the group with a decreased number of one line and the other two groups with a normal number of three lines and the group with at least one increased number of three lines(P＞0.05).The missed rates of hemophagocytes in the five groups were 15.78％,22.03％,62.22％,77.78％and 53.84％,respectively.Conclusion:For patients with fever of unknown origin,especially those with obvious decrease in the number of three lines and two lines in peripheral blood cells,which should pay attention to the detection of hemophagocytes in bone marrow.Meanwhile,if the number of three lines was normal even at least one of the three lines increased,the presence of hemophagocytes in the bone marrow slice should be also carefully observed.
