Research progress on alterations in host signaling pathways triggered by porcine parvovirus infection
10.16303/j.cnki.1005-4545.2024.10.27
- VernacularTitle:猪细小病毒感染引起宿主信号通路变化的研究进展
- Author:
Min ZHOU
1
;
Deyuan TANG
;
Zhiyong ZENG
;
Bin WANG
;
Tao HUANG
;
Wenwen HU
;
Yinming MAO
;
Piao ZHOU
;
Song HE
Author Information
1. 贵州大学动物科学学院,贵州贵阳 550025
- Keywords:
porcine parvovirus;
reproductive disorders;
signal pathways;
pathogenic mechanism
- From:
Chinese Journal of Veterinary Science
2024;44(10):2294-2300
- CountryChina
- Language:Chinese
-
Abstract:
Porcine parvovirus(PPV)is a causative agent of porcine parvovirus infection(PPI),which significantly impacts the pig industry due to its association with reproductive dysfunction.The condition is characterized by stillbirth,mummified fetuses,fetal weakness,and abortion in pregnant sows.The pathogenic mechanism remains incompletely understood,with no effective therapeutic drugs available currently.Despite extensive research on the host's response to PPV in-fection and identification of various signaling pathway transduction mechanisms,a comprehensive understanding is still lacking.This review aims to summarize the current knowledge regarding al-terations in related signaling pathways following PPV infection,provide novel insights into the pathogenesis of PPV and facilitate the drug development.
