Effects of agaric polysaccharides on antioxidant capacity,serum immune indexes and intestinal flora of calves
10.16303/j.cnki.1005-4545.2024.06.25
- VernacularTitle:木耳多糖对犊牛血清抗氧化、免疫指标及肠道菌群的影响
- Author:
Qiru WANG
1
;
Yu ZHANG
;
Guojun JIANG
;
Haiyan LIU
;
Xin HE
;
Xinchao SHI
;
Xing-Hua ZHAO
Author Information
1. 河北农业大学 动物医学(中兽医)学院,河北 保定 071001
- Keywords:
agaric polysaccharides;
calves;
antioxidant capacity;
immune function,intestinal flora
- From:
Chinese Journal of Veterinary Science
2024;44(6):1290-1298
- CountryChina
- Language:Chinese
-
Abstract:
This experiment was conducted to investigate the effects of agaric polysaccharides on an-tioxidant capacity,immune function,and intestinal flora of calves.Twenty-four healthy Holstein calves of(30±3)days of age and with the similar body weight at(55.33±1.86)kg were selected and randomly divided into two groups:the control group(group C)and test group(group T)with 12 replicates in each group and one calves in each replicate.Group C was fed starter and milk repla-cer,and group T was fed starter and milk replacer with 10 g of agaric polysaccharides to each calve for 10 d.Serum antioxidant,immune indexes and intestinal flora were tested.The results showed as follows:compared with group C,the enzyme activities of SOD and GSH-Px in serum of calves in group T were significantly increased(P＜0.05),and were increased by 29.09％and 15.35％,re-spectively;compared with group C,IgA,IL-2 and TNF-α were significantly increased in T group(P＜0.05).Adding agaric polysaccharides significantly increased the relative abundance of Firmi-cutes(P＜0.05)and decreased the relative abundance of Proteobacteria in feces of calf(P＞0.05);the relative abundance of Lactobalillus and Faecalibacterium were increased(P＜0.05);the relative abundance of Butyricoccus-pullicaecorum was increased(P＜0.05).LEfSe analysis results showed that there were 11 marker species in group T,such as Firmicutes and Lactobacillus,and 9 marker species in group C,such as Proteobacteria.The results showed that agaric polysaccharides could improve the antioxidant capacity and immune function of calves,and also could improve the structure of intestinal flora.
