Overview of traditional Chinese medicine's role in regulating the mechanism of regulatory cell death in vascular dementia

VernacularTitle:调节性细胞死亡在血管性痴呆中的作用及中医药调控机制概述
Author: Hui LI ¹ ; Xingang DONG ; Weifeng LI
Author Information

1. 河南中医药大学康复医学院,郑州 450046
Keywords: vascular dementia; regulatory cell death; crosstalk; ferroptosis; cuproptosis; traditional Chinese medicine prevention and treatment
From: Chinese Journal of Comparative Medicine 2024;34(9):146-156
CountryChina
Language:Chinese
Abstract: Vascular dementia(VD)is a neurodegenerative disease caused by brain injury.Research on the processes leading to its occurrence is lacking depth.In recent years,it has been proposed that regulatory cell death(RCD)mechanisms,including apoptosis,pyroptosis,autophagy,ferroptosis,and cuproptosis,are related to the pathological mechanisms of VD.Therefore,studies aiming to explain the links between the mechanisms of regulatory death and the pathology of VD would be beneficial to our understanding of VD.This article provides a review of the roles of five mechanisms of RCD in VD and summarizes the recent progress made in researching the treatment of VD with traditional Chinese medicine,providing a resource for the development of new traditional Chinese medicine drugs.