Analysis of the construction and practice of an animal biosafety level-3 simulated laboratory
10.3969/j.issn.1671-7856.2024.06.011
- VernacularTitle:动物生物安全三级模拟实验室的建设与实践探讨
- Author:
Yushan ZAINAWUDONG
1
;
Xiaoyan LI
;
Shuangshuang LU
;
Jiaqi WANG
;
Aimulajiang KALIBIXIATI
;
Mei LIU
;
Keliang LIU
;
Xuancheng LU
Author Information
1. 传染病溯源预警与智能决策全国重点实验室,中国疾病预防控制中心,北京 102206
- Keywords:
ABSL-3 laboratory;
ABSL-3 simulated laboratory;
laboratory acquired infection;
biosafety;
risk assessment;
training
- From:
Chinese Journal of Comparative Medicine
2024;34(6):87-92
- CountryChina
- Language:Chinese
-
Abstract:
An animal biosafety level-3 laboratory(ABSL-3)is a high-level biosafety installation that can conduct experiments on animals infected with highly pathogenic microorganisms.In recent years,with the continuous characterization of emerging and re-emerging infectious diseases,high-level biosafety laboratories have played increasingly important roles in pathogenic mechanism and drug and vaccine research and development.The demand for ABSL-3 is increasing year by year.At the same time,there is also a growing demand for personnel who are competent in working in ABSL-3.The systematization,normalization,and standardization of pre-service training have become important to guarantee a reduction in the risks to personnel working in ABSL-3.Training of ABSL-3 staff needs to be carried out in specific simulated laboratories.Therefore,it is necessary to construct simulated ABSL-3 and establish scientific and effective operating standards and mechanisms.This paper comprehensively introduces the design,construction,operation,and functions of a simulated ABSL-3 installation.
