Research progress in constructing animal models of steroid-induced osteonecrosis of the femoral head
10.3969/j.issn.1005-4847.2024.10.013
- VernacularTitle:激素性股骨头坏死动物模型构建的研究进展
- Author:
Yang LEI
1
;
Huiying LI
;
Dongfang MENG
;
Xiangbei ZHANG
;
Kai WANG
Author Information
1. 河南中医药大学,郑州 450046
- Keywords:
SONFH;
animal models;
model construction;
model evaluation;
molding method
- From:
Acta Laboratorium Animalis Scientia Sinica
2024;32(10):1352-1360
- CountryChina
- Language:Chinese
-
Abstract:
As a complex and refractory disease,the incidence of steroid-induced osteonecrosis of the femoral head(SONFH)is increasing year by year and showing an increasing trend in younger people.A good animal model of disease can provide important support for studying the pathogenesis of SONFH and the development of treatment method.In this paper,the latest progress made in the construction of SONFH animal models is summarized and analyzed from the aspects of animal selection,modeling method,and model evaluation.To achieve this,we review and categorize the experimental studies related to SONFH animal models conducted in China and overseas in recent years,providing a reference for related research of SONFH.
