Research progress in animal models of audiogenic seizures

VernacularTitle:听源性癫痫动物模型研究进展
Author: Wenji ZHAI ¹ ; Jie WU ; Tihua ZHENG ; Qingyin ZHENG
Author Information

1. 滨州医学院特殊教育与康复学院,山东烟台 264003
Keywords: audiogenic seizures; animal model; antiepileptic drugs
From: Acta Laboratorium Animalis Scientia Sinica 2024;32(6):786-792
CountryChina
Language:Chinese
Abstract: Audiogenic seizures(AGS)are the result of an epilepsy caused by strong acoustic stimulation and are characterized by generalized muscle spasms.AGS models are vital for studies of epileptogenesis,the search for causative genes and regulatory channels,and the screening of new antiepileptic drugs(AEDs).This paper summarizes the current progress of research on common animal models of AGS in terms of their pathogenetic features,possible pathogenesis,and causative genes to provide new research directions and targets for the development of AEDs.