Advances in animal models of intestinal fibrosis
10.3969/j.issn.1005-4847.2024.05.014
- VernacularTitle:肠纤维化动物模型研究进展
- Author:
Xi WANG
1
;
Hao LIU
;
Xinyu SHEN
;
Xin SUN
;
Defang ZOU
;
Renjun GU
Author Information
1. 南京中医药大学第一临床医学院,南京 210023
- Keywords:
intestinal fibrosis;
animal model;
model characteristic
- From:
Acta Laboratorium Animalis Scientia Sinica
2024;32(5):666-675
- CountryChina
- Language:Chinese
-
Abstract:
Intestinal fibrosis is a complication of inflammatory bowel disease,and its refractory and recurrent nature impose a serious disease burden on patients.The disease's pathogenes is not clear,and there is no effective treatment.Moreover,there is still a lack of recognized intestinal fibrosis models.In this paper,we review the method used to establish animal models of intestinal fibrosis both at home and abroad,and consider the clinical relevance,key characteristics,and advantages and disadvantages of the procedures.Intestinal fibrosis models were summarized according to the modeling period and method.
