Research progress in mouse models of sarcopenia
10.3969/j.issn.1005-4847.2024.03.015
- VernacularTitle:肌少症小鼠模型的研究进展
- Author:
Xinao JIA
1
,
2
;
Yujiao TANG
Author Information
1. 吉林省中韩动物科学研究院,长春 130600
2. 吉林农业大学食品科学与工程学院,长春 130118
- Keywords:
sarcopenia;
animal model;
skeletal muscle aging;
modeling method
- From:
Acta Laboratorium Animalis Scientia Sinica
2024;32(3):404-410
- CountryChina
- Language:Chinese
-
Abstract:
We searched the literature related to sarcopenia to retrieve information on modeling method and model-evaluation schemes using sarcopenic mice.Here,we review the operation method,advantages and disadvantages,and application scopes of the four modeling method,including drug injection,aging,muscle atrophy,and transgenic mice,and summarize the method used to evaluate muscle function,muscle strength,and muscle endurance.We then compare their advantages and disadvantages,to provide a reference for subsequent research into sarcopenia.
