Construction of experimental animal models and evaluation of spleen deficiency syndrome:a review
10.3969/j.issn.1005-4847.2024.03.013
- VernacularTitle:脾虚证实验动物模型构建及评价方法的研究述评
- Author:
Yonglong ZHANG
1
;
Weigang MA
;
Xingyu QIAN
;
Suhong ZHAO
;
Shanshan LI
;
Yongming GUO
;
Zhifang XU
;
Xingfang PAN
;
Jiwen QIU
;
Yi GUO
;
Zhongzheng LI
Author Information
1. 天津中医药大学实验针灸学研究中心,天津 301617
- Keywords:
spleen deficiency;
animal models;
evaluation methods;
review
- From:
Acta Laboratorium Animalis Scientia Sinica
2024;32(3):385-396
- CountryChina
- Language:Chinese
-
Abstract:
The construction of experimental animal models plays an important supporting role in research into the mechanisms of action of Chinese medicines.There have been increasing reports of the construction and evaluation of animal models of spleen deficiency;however,the construction method have involved different standards and there has been insufficient objectification of the evaluation indexes.In this review,we summarize the construction and evaluation method of animal models of spleen deficiency from the aspects of animal selection,model establishment,macroscopic characterization,behavioral experiments,and objective indexes of spleen deficiency,with a view to providing theoretical guidance for the construction of experimental animal models of spleen deficiency and references for the selection of animal model platforms for spleen deficiency.
