Differentiation and function of presynaptic active zone
- VernacularTitle:突触前活动区的分化与功能
- Author:
Shen LU-LU
1
;
Wang DA-YONG
Author Information
1. Southeast University Medical School
- Keywords:
active zone;
differentiation;
structure;
function;
regulating mechanism
- From:
Neuroscience Bulletin
2005;21(5):335-343
- CountryChina
- Language:Chinese
-
Abstract:
Neurotransmitter release during synaptic transmission is mediated by presynaptic active zone. Multiple protein components at the active zone region interact and coordinate with each other to control and regulate docking, priming and fusion of the synaptic vesicles with presynaptic membrane, and to further maintain the normal transmitter release process. This review will discuss the structure, the formation, and the functional regulation of active zones.
