The function of nucleus accumbens in drug addiction
- VernacularTitle:伏核在药物成瘾中的作用
- Author:
Heng LI-JUN
1
;
Gao GUO-DONG
Author Information
1. 第四军医大学
- Keywords:
nucleus accumbens;
drug tolerance;
substance withdrawal syndrome;
substance-related disorders
- From:
Neuroscience Bulletin
2005;21(2):165-169
- CountryChina
- Language:Chinese
-
Abstract:
Nucleus accumbens, an important component of brain-reward regions, is involved in the reinforcement, tolerance, addiction and expression of withdrawal syndrome of drug addiction. Previous studies of nucleus accumbens in functional anatomy, receptor activation and signal transduction, gene transcription and molecular expression, neuronal plasticity and changes in behavior help us understand the mechanism of drug addiction in the central nervous system, and provide us with basic principles for clinical treatment of drug withdrawal syndrome.
