Progress of long chain non-coding RNAs in the inflammatory response to cerebral ischemia-reperfusion in-jury
10.3969/j.issn.1002-0152.2024.05.010
- VernacularTitle:长链非编码RNA在脑缺血再灌注损伤炎症反应中研究进展
- Author:
Lei LI
1
;
Xinrui LI
;
Ying WANG
;
Chuyan LI
;
Yuhong ZHU
Author Information
1. 昆明医科大学第二附属医院神经内科(昆明 650032)
- Keywords:
Long non-coding RNA;
MicroRNA;
Cerebral ischemia-reperfusion injury;
Inflammatory response
- From:
Chinese Journal of Nervous and Mental Diseases
2024;50(5):305-309
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory response is one of the key mechanisms of cerebral ischemia/reperfusion injury(CIRI),which seriously affects the prognosis of patients.In recent years,it has been found that long non-coding RNA(LncRNA)is closely related to the inflammatory response of cerebral ischemia/reperfusion injury,and can affect the development and prognosis of CIRI through multiple pathways.The article reviews and summarizes the LncRNAs and their action pathways affecting the inflammatory response in CIRI.The article preliminary explores the possible mechanisms by which LncRNAs affect CIRI,and also briefly summarizes the drugs related to LncRNA therapy.In order to provide new therapeutic targets and research ideas for the treatment of CIRI.
