Clinical characteristics of 30 patients with intracranial hypotension syndrome
10.3969/j.issn.1002-0152.2024.05.002
- VernacularTitle:30例低颅压综合征临床特点分析
- Author:
Siqi WENG
1
;
Yanan CAI
;
Sichen HE
;
Guohui HUANG
;
Zihui DENG
;
Bin CHEN
;
Xiaojun LIU
;
Suyue PAN
;
Yabin JI
Author Information
1. 南方医科大学南方医院神经内科(广州 510515)
- Keywords:
Intracranial hypotension syndrome;
Clinical picture;
Headache;
Cerebrospinal fluid leakage;
Mag-netic resonance imaging;
Retrospective analysis;
CT myelography
- From:
Chinese Journal of Nervous and Mental Diseases
2024;50(5):263-267
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze and summarize the clinical presentation of spontaneous and secondary intracranial hypotension syndrome(IHS).Methods Patients diagnosed with spontaneous or secondary IHS from September 2022 to May 2023 were retrospectively analyzed.The clinical data,imaging features,treatment methods and prognosis were collected.The correlation between intracranial pressure values and clinical characteristics of the patients was statistically analyzed.Results A total of 30 patients were enrolled,and the proportion of spontaneous and secondary IHS was 63%(19 cases)and 37%(11 cases),respectively.In terms of clinical features,orthostatic headache was the most common type(29 cases,96.7%)and most commonly involved occipital region(12 cases,40.0%),followed by frontoparietal region(9 cases,30.0%).Among the brain imaging features,dural enhancement was the most common(17 cases,56.7%).According to CT angiography of spinal cord findings,cerebrospinal fluid leakage is one of the most common location of cervical spine segments(10 cases),and on the thoracic segments(9 cases),followed by the thoracic segments(4 cases)and lumbar segments(4 cases).After conservative treatment and surgical treatment,the total effective rate was 90%.Conclusion Orthostatic headache and cranial MRI"dural enhancement"have strong indication on the definitive diagnosis of IHS.CT myelography is helpful to precisely localize the site of cerebrospinal fluid leakage.Targeted epidural blood patch therapy is an effective method to cure IHS when conservative treatment is ineffective.
