Research progress on the correlation between imaging markers and cognitive dysfunction in cerebral small vessel disease

VernacularTitle:脑小血管病影像学标志物与认知功能障碍相关性研究进展
Author: Nan XING ^{1
,

2} ; Suyu HUA ; Litao LI
Author Information

1. 华北理工大学研究生院(唐山 063210)
2. 河北省人民医院神经内六科
Keywords: Cerebral small vessel disease; Imaging markers; White matter hyperintensity; Enlarged perivascular space; Cerebral microbleedings; Lacunar infarction; Cognitive function
From: Chinese Journal of Nervous and Mental Diseases 2024;50(4):242-246
CountryChina
Language:Chinese
Abstract: Some patients with cerebral small vessel disease(CSVD)may experience cognitive decline and may progress to dementia,which seriously impairs the quality of life of patients.Current studies on the correlation between CSVD imaging markers and cognitive impairment have shown that the distribution and severity of white matter hyperintensity(WMH),enlarged perivascular spaces(EPVS),cerebral microbleeds(CMB),and lacunar infarction(LI)have different effects on various cognitive domains.The cognitive dysfunction caused by CSVD may be related to indirect effects of inflammatory factors and damage to the brain tissue fiber bundles.However,the relationship between CSVD imaging markers and cognitive function and its related mechanisms still need to be further studied and verified.