A Case of Nonfunctioning Pancreatic Islet Cell Carcinomas in Adolescence.
- Author:
Seok Yun LEE
1
;
Dong Eun PARK
;
Kwon Mook CHAE
Author Information
1. Department of surgery, Wonkwang University College of Medicine, Iksan, Korea. knife@wonkwang.ac.kr
- Publication Type:Case Report
- Keywords:
Pancreas;
Carcinoma;
Islet Cell
- MeSH:
Abdomen;
Abdominal Pain;
Adenoma, Islet Cell;
Adolescent*;
Biopsy;
Carcinoma, Islet Cell;
Child;
Decarboxylation;
Diarrhea;
Drug Therapy;
Head;
Humans;
Islets of Langerhans*;
Pancreas;
Vomiting
- From:Korean Journal of Hepato-Biliary-Pancreatic Surgery
2006;10(1):41-46
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neuroendocrine pancreatic tumors (NPTs) arise from the pancreatic islet cells and belong to the amine and precursor uptake and decarboxylation (APUD) system. These tumors are rare and account for only 1% to 5% of pancreatic tumor. The pancreas is an extremely uncommon site of neoplasia in children and adolescents. For this reason, our understanding of these tumors is still quite limited. Although the complete surgical resection is the key to successful management of all malignant adolescence pancreatic tumors, the information on the possible role of chemotherapy and radiation in recurrent, unresectable, or metastatic cases is purely anecdotal. The 17-year-old man transferred to our hospital with abnormal ultrasonographic findings. Result of abdominal ultrasonographic examination showed a mass in the upper abdomen. He presented with 6months history of intermittent abdominal pain and vomiting and diarrhea. A computed tomography (CT) scan and magnetic resonance showed a 4.5 x 6 cm mass in the head of the pancreas. An ultrasound-guided core biopsy confirmed an pancreatoblastoma or pancreas islet cell tumor. On operative findings, there was locally advanced, unresectable tumor within the pancreatic head. We report a 17-years-old man patient with non-functional panceratic islet cell carcinoma.
