A case report of COVID-19-associated acute necrotizing encephalopathy
10.3969/j.issn.1002-0152.2024.03.006
- VernacularTitle:新型冠状病毒感染相关急性坏死性脑病1例
- Author:
Li ZHAO
1
;
Xianzhi LI
;
Liting YAN
;
Yi LI
;
Xiaoqi WANG
;
Xiao YANG
Author Information
1. 宁夏医科大学总医院神经内科(银川 750000)
- Keywords:
SARS-CoV-2;
Acute necrotic encephalopathy;
COVID-19-associated acute necrotizing encepha-lopathy;
Disturbance of consciousness;
Epilepsy;
Thalamic lesion;
Prognosis
- From:
Chinese Journal of Nervous and Mental Diseases
2024;50(3):156-158
- CountryChina
- Language:Chinese
-
Abstract:
This article reports one case of adult COVID-19-associated acute necrotizing encephalopathy(ANEC).The patient developed disturbance of consciousness and seizure on the 12th day after SARS-CoV-2 infection.Imaging showed significant swelling and signal changes in the bilateral thalamus,brainstem,cerebral hemisphere and cerebellar hemisphere,which were consistent with the characteristic images of Acute necrotizing encephalitis(ANE).Although methylprednisolone shock therapy and high-dose human immunoglobulin therapy were given early,the patient died.ANEC often starts quickly and progresses rapidly,unconsciousness and seizure are the main manifestations.Imaging features of thalamic and subtentorial symmetry and multifocal lesions are specific for diagnosis,but the treatment and prognosis still face challenges and need further study.
